Menu
Lee, Y. et al. Roles of sarcoplasmic reticulum Ca2+-ATPase pump in the impairments of lymphatic contractile activity in a metabolic syndrome rat model. Sci. Rep. 2020, 105, 12320.
Singh, R. et al. A role for calcium in resistin transcriptional activation in diabetic hearts. Sci. Rep. 2018, 8, 15633.
Yuan, L. et al. Etoposide-induced protein 2.4 functions as a regulator of the calcium ATPase and protects pancreatic β-cell survival. J. Biol. Chem. 2018, 293, 10128–10140.
Kang, S. et al. Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders. J. Biol. Chem. 2016, 291, 5185-5198.
Tong, X. et al. SERCA2 Deficiency Impairs Pancreatic β-Cell Function in Response to Diet-Induced Obesity. Diabetes. 2016, 65, 3039–3052.
Nogami, K. et al. Pharmacological activation of SERCA ameliorates dystrophic phenotypes in dystrophin-deficient mdx mice. Hum. Mol. Genet. 2021, 30, 1006-1019.
Lindsay, A. et al. Mechanical Factors Tune the Sensitivity of Mdx Muscle to Eccentric Strength Loss and Its Protection by Antioxidant and Calcium Modulators. Skelet. Muscle 2020, 10, 3.
Qaisar, R. et al. Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weakness. Redox Biol. 2019, 20, 68-74.
Van Remmen, H. et al. SERCA activation as an intervention to reduce muscle atrophy and weakness. Innov. Aging. 2018, 2, 347.
Mengeste, A.M. et al. The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells. Curr. Res. Pharmacol Drug Discov. 2021, 2, 100060.
Qaisar, R. et al. Restoration of Sarcoplasmic Reticulum Ca2+-ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice. Int J. Mol. Sci, 2020, 22, 37.
Solana-Manrique, C. et al. Oxidative modification impairs SERCA activity in Drosophila and human cell models of Parkinson’s disease. Biochim Biophys Acta Mol. Basis Dis., 2021, 1867, 166152.
Dahl, R. A new target for Parkinson’s disease: Small molecule SERCA activator CDN1163 ameliorates dyskinesia in 6-OHDA-lesioned rats. Bioorg. Med. Chem. 2017, 25, 53-57.
Krajnak, K. & Dahl, R. A new target for Alzheimer’s disease: A small molecule SERCA activator is neuroprotective in vitro and improves memory and cognition in APP/PS1 mice. Bioorg. Med. Chem. Lett. 2018, 28, 1591-1594.
Krajnak, K. & Dahl, R. Small molecule SUMOylation activators are novel neuroprotective agents. Bioorg. Med. Chem. Lett. 2018, 28, 405-409.
Qaisar, R. et al. Restoration of Sarcoplasmic Reticulum Ca2+-ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice. Int. J. Mol. Sci, 2020, 22, 37.
Kong, A. et al. Cadmium induces triglyceride levels via microsomal triglyceride transfer protein (MTTP) accumulation caused by lysosomal deacidification regulated by endoplasmic reticulum (ER) Ca2+ homeostasis. Chem. Biol. Interact. 2021, 348, 109649.
Li, S. et al. Neonicotinoid insecticides triggers mitochondrial bioenergetic dysfunction via manipulating ROS-calcium influx pathway in the liver. Ecotoxicol. Environ. Saf. 2021, 224, 112690.
Li, J. et al. Deletion of Tmtc4 activates the unfolded protein response and causes postnatal hearing loss. J. Clin. Invest. 2018, 128, 5150–5162.
Peng, J. et al. Sarco/Endoplasmic Reticulum Ca2+ Transporting ATPase (SERCA) Modulates Autophagic, Inflammatory, and Mitochondrial Responses during Influenza A Virus Infection in Human Lung Cells. J. Virol, 2021, 95, e00217-21.
Li, S. et al. Sarco/endoplasmic reticulum Ca2+-ATPase 2b mediates oxidation-induced endoplasmic reticulum stress to regulate neuropathic pain. Br. J. Pharmacol. 2021, published online Nov. 22, 2021.