At Neurodon, we treat cellular stress at the root of many diseases; we create disease-modifying therapeutics with the potential to change patients’ lives.
Calcium balance in cells, while inconspicuous, is critical for maintaining overall health and fighting disease. Disruption of normal intracellular calcium levels triggers the endoplasmic reticulum (ER) stress pathway that leads to cell dysfunction, encompassing impaired signaling, respiration, protein processing, and eventual cell death. This drives the progression of many diseases related to the stress pathway such as diabetes, Alzheimer’s, Parkinson’s, and Duchenne muscular dystrophy. Our research works to regulate impaired transport of cellular calcium to relieve stress pathways.
At Neurodon, we target the source of cellular stress pathways to provide disease-modifying effects and revolutionize medicine.
Through many years of research, our team has been developing our proprietary small molecules that allosterically modulate the SERCA enzyme conformation to accelerate calcium transport into the ER.
We are excited to announce the success of our small molecule therapeutics using research that has been in development for decades.